Carlos Pacheco began his career working for Planeta De Agostini Comics in Europe. He later co-created the Spanish superheroes Iberia Inc. and Tríada Vértice along with writer Rafael Marin.
Pacheco first got attention in the United States for pencilling the title Dark Guard, working alongside inker Oscar Jimenez and writer Dan Abnett. He would later pencil the mini series Bishop for Marvel Comics and three issues of The Flash for DC Comics. His next work within the United States was in the two part limited series X-Universe and the limited series Starjammers. By that point, Pacheco's art had become very popular amongst fans, leading to him being given multiple assignments by Marvel, DC, and Wildstorm.